Anti-Human CD355/CRTAM Recombinant Antibody (5A11) (HF645107)

Name: Anti-Human CD355/CRTAM Recombinant Antibody (5A11)
Brand: abinScience
SKU: HF645107
Price: 191 USD
Availability: InStock

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Обзор

Каталожный номер	HF645107
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	5A11
Цель	Class-I MHC-restricted T-cell-associated molecule, Cytotoxic and regulatory T-cell molecule, CD355, CRTAM
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	O95727
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Cytotoxic and regulatory T-cell molecule (CD355/CRTAM) is a ~44 kDa protein. Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T-cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. Regulates CD8+ T-cell proliferation in response to T-cell receptor (TCR) activation. Appears to be dispensable for CD8+ T-cell-mediated cytotoxicity. Interaction with SCRIB promotes the late phase of cellular polarization of a subset of CD4+ T-cells, which in turn regulates TCR-mediated proliferation and IFNG, IL17 and IL22 production. 1. Boles, KS. et al. (2005) Blood 106, 779-86. PMID: 15811952
Примечание	For research use only.

Изображения

Bioactivity

Detects CD355/CRTAM in indirect ELISAs.
Western blot

Western blot analysis was performed using anti-CD355/CRTAM monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD355/CRTAM (Catalog No: HF645011)
Lane 2: negative control

Ссылки

Даташит

Anti-Human CD355/CRTAM Recombinant Antibody (5A11).pdf

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