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Anti-Human TIM-3 Recombinant Nanobody (R53)
Anti-Human TIM-3 Recombinant Nanobody (R53)
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Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
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Обзор
Каталожный номерHV029023
Описание
Anti-Human CD366/HAVCR2/TIM-3 Nanobody (R53) [R53] (HV029023) is a alpaca monoclonal antibody detecting HAVCR2 in ELISA, FCM. Suitable for Human.
Highlights
  • ●Flow Cytometry — Validated for flow cytometry applications.
Реактивность видовHuman
ПримененияELISA, FCM
Хозяинский видAlpaca
КлоональностьMonoclonal
ИзотипVHH-8His-Cys-tag
ID клонаR53
Цель CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Purified by Nickel column
Номер доступа Q8TDQ0
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Hepatitis A virus cellular receptor 2 (CD366/TIM-3) is a ~33 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Gorman, JV. et al. (2014) Immunologic research 59, 56-65. PMID: 24825777
2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861
3. Sánchez-Fueyo, A. et al. (2003) Nature immunology 4, 1093-101. PMID: 14556005
4. Clayton, KL. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 782-91. PMID: 24337741
5. Tomkowicz, B. et al. (2015) PloS one 10, e0140694. PMID: 26492563
6. Gautron, AS. et al. (2014) European journal of immunology 44, 2703-2711. PMID: 24838857
7. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920
8. Leitner, J. et al. (2013) PLoS pathogens 9, e1003253. PMID: 23555261
9. Gleason, MK. et al. (2012) Blood 119, 3064-72. PMID: 22323453
Примечание For research use only.
Изображения
  • Anti-Human TIM-3 Recombinant Nanobody (R53)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD366/HAVCR2/TIM-3 Nanobody (R53)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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