Anti-Human CD37 Recombinant Antibody (SAA2108) (HY564023)

Name: Anti-Human CD37 Recombinant Antibody (SAA2108)
Brand: abinScience
SKU: HY564023
Price: 126 USD
Availability: InStock

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20ug
50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HY564023

Reactivité des espèces

Human

Applications

ELISA, WB

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG1, kappa

ID de clone

SAA2108

Applications testées

Cible

Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P11049

RRID

Anti-Human CD37/TSPAN26 Antibody (SAA2108) (abinScience Cat# HY564023, RRID:AB_3729395)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role essential for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT.

1. Lapalombella, R. et al. (2012) Cancer cell 21, 694-708. PMID: 22624718

2. de Winde, CM. et al. (2016) The Journal of clinical investigation 126, 653-66. PMID: 26784544

3. Meyer-Wentrup, F. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 154-62. PMID: 17182550

Note

For research use only.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

Bioactivity

SEC-HPLC detection for Anti-Human CD37/TSPAN26 Antibody (ABS1208).
SDS-PAGE

SDS-PAGE for Anti-Human CD37/TSPAN26 Antibody (SAA2108).
Western blot

Western blot analysis was performed using anti-CD37 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD37 (Catalog No: HY564012)
Lane 2: negative control
Bioactivity

Detects recombinant human CD37 (Catalog No: HY564012) in indirect ELISA