Anti-Human CD37 Recombinant Antibody (SAA2108) (HY564023)

Name: Anti-Human CD37 Recombinant Antibody (SAA2108)
Brand: abinScience
SKU: HY564023
Price: 126 USD
Availability: InStock

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Цена(USD):

Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HY564023

Реактивность видов

Human

Применения

ELISA, WB

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

SAA2108

Проверенные приложения

Цель

Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P11049

RRID

Anti-Human CD37/TSPAN26 Antibody (SAA2108) (abinScience Cat# HY564023, RRID:AB_3729395)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role essential for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT.

1. Lapalombella, R. et al. (2012) Cancer cell 21, 694-708. PMID: 22624718

2. de Winde, CM. et al. (2016) The Journal of clinical investigation 126, 653-66. PMID: 26784544

3. Meyer-Wentrup, F. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 154-62. PMID: 17182550

Примечание

For research use only.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

Bioactivity

SEC-HPLC detection for Anti-Human CD37/TSPAN26 Antibody (ABS1208).
SDS-PAGE

SDS-PAGE for Anti-Human CD37/TSPAN26 Antibody (SAA2108).
Western blot

Western blot analysis was performed using anti-CD37 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD37 (Catalog No: HY564012)
Lane 2: negative control
Bioactivity

Detects recombinant human CD37 (Catalog No: HY564012) in indirect ELISA