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Anti-Human CD4 Recombinant Antibody (OKT4A), APC (HF998337)

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概要
カタログ番号HF998337
種反応性Human
アプリケーションFCM, IF
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG2a, kappa
クローンIDOKT4A
抱合APC
ターゲット CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
関連製品 Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
アクセッション番号 P01730
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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