Anti-Human CD40/TNFRSF5 Recombinant Antibody (SAA1387) (HB782307)

Name: Anti-Human CD40/TNFRSF5 Recombinant Antibody (SAA1387)
Brand: abinScience
SKU: HB782307
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HB782307
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	SAA1387
Aplicaciones probadas	FCM
Objetivo	B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P25942
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
Nota	For research use only.

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Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.
Flow Cytometry

Flow-cytometry using anti-human CD40 antibody.Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD40 antibody monoclonal antibody (Catalog # HB782307 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.