Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25), APC (HY355637)

Name: Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25), APC
Brand: abinScience
SKU: HY355637
Price: 290 USD
Availability: InStock

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Número de catálogo	HY355637
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	PT25
Conjugación	APC
Objetivo	CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Número de acceso	P08514
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Integrin alpha-IIb (CD41/ITGA2B) is a ~113 kDa protein. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. 1. Si-Tahar, M. et al. (1997) The Journal of biological chemistry 272, 11636-47. PMID: 9111081 2. Hermand, P. et al. (2003) The Journal of biological chemistry 278, 4892-8. PMID: 12477717
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25), APC.pdf

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