





| Número de catálogo | HY195023 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-Human CD45/PTPRC Nanobody (2H7) [2H7] (HY195023) is a alpaca monoclonal antibody detecting Ptprc in ELISA, SPR. Suitable for Human.
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| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA, SPR | ||||
| Especie huésped | Alpaca | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | VHH-8His-Cys-tag | ||||
| ID de clon | 2H7 | ||||
| Objetivo | Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | P06800 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Receptor-type tyrosine-protein phosphatase C (CD45/PTPRC) is a ~144 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human CD45/PTPRC Nanobody (2H7)

Detects recombinant CD45 (Catalog No: HY195011) in indirect ELISA.

Immunofluorescence staining of Jurkat with Alpaca monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the Cell membrane.




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