Anti-Human CD45RO Recombinant Antibody (UCHL1), APC (HY195337)

Name: Anti-Human CD45RO Recombinant Antibody (UCHL1), APC
Brand: abinScience
SKU: HY195337
Price: 256 USD
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Número de catálogo	HY195337
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Rabbit
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	UCHL1
Conjugación	APC
Objetivo	T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Rabbit IgG Recombinant Isotype Control Antibody (HyHEL-10), APC
Número de acceso	P08575
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Receptor-type tyrosine-protein phosphatase C (CD45RO) is a ~147 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. 1. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.