Anti-Human CD45 Recombinant Antibody (UCHL1) (HY195307)

Name: Anti-Human CD45 Recombinant Antibody (UCHL1)
Brand: abinScience
SKU: HY195307
Price: 196 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HY195307
Reactivité des espèces	Human
Applications	FCM
Espèce hôte	Rabbit
Clonalité	Monoclonal
Isotype	IgG
ID de clone	UCHL1
Cible	T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P08575
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.09% Sodium azide. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Receptor-type tyrosine-protein phosphatase C (CD45RO) is a ~147 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. 1. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951
Note	For research use only.