Anti-Human CD45 Recombinant Antibody (UCHL1) (HY195307)

Name: Anti-Human CD45 Recombinant Antibody (UCHL1)
Brand: abinScience
SKU: HY195307
Price: 196 USD
Availability: InStock

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概要

カタログ番号	HY195307
種反応性	Human
アプリケーション	FCM
宿主種	Rabbit
クローン性	Monoclonal
アイソタイプ	IgG
クローンID	UCHL1
ターゲット	T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P08575
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.09% Sodium azide. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Receptor-type tyrosine-protein phosphatase C (CD45RO) is a ~147 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. 1. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951
注意事項	For research use only.