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Anti-Human CD46 Recombinant Antibody (035-224#), FITC (HB735117)

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Vista general
Número de catálogoHB735117
Reactividad de especiesHuman
AplicacionesFCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clon035-224#
ConjugaciónFITC
Objetivo Trophoblast leukocyte common antigen, CD46, TLX, MCP, Membrane cofactor protein, MIC10
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
Número de acceso P15529
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.

Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Working Solution
C₂ (Working Conc.)
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