Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7), APC (HB114137)

Name: Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7), APC
Brand: abinScience
SKU: HB114137
Price: 256 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HB114137
種反応性	Human
アプリケーション	ELISA, FCM, WB
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	84H7
抱合	APC
ターゲット	ITGA3, CD49 antigen-like family member C, VLA-3 subunit alpha, GAPB3, CD49c, FRP-2, Integrin alpha-3, MSK18, Galactoprotein B3
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
アクセッション番号	P26006
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Integrin alpha-3 (CD49c/ITGA3) is a ~116 kDa protein. Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow CytoMetry

Flow-cytometry using APC anti-human CD49c antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD49c monoclonal antibody (Catalog: HB114137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献

データシート