





| Número de catálogo | HB114107 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FCM, IP, WB |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | 84H7 |
| Objetivo | ITGA3, CD49 antigen-like family member C, VLA-3 subunit alpha, GAPB3, CD49c, FRP-2, Integrin alpha-3, MSK18, Galactoprotein B3 |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P26006 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Fondo | Integrin alpha-3 (CD49c/ITGA3) is a ~116 kDa protein. Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Nota | For research use only. |

Flow-cytometry using anti-human CD49c antibody.HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

Flow-cytometry using anti-human CD49c antibody.KG-1 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

Flow-cytometry using anti-human CD49c antibody.MG-63 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.




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