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Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7) (HB114107)

Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
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Aperçu
Numéro de catalogueHB114107
Reactivité des espècesHuman
ApplicationsELISA, FCM, IP, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de clone84H7
Cible ITGA3, CD49 antigen-like family member C, VLA-3 subunit alpha, GAPB3, CD49c, FRP-2, Integrin alpha-3, MSK18, Galactoprotein B3
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P26006
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Integrin alpha-3 (CD49c/ITGA3) is a ~116 kDa protein. Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Note For research use only.
Images
  • Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)

    Flow Cytometry

    Flow-cytometry using anti-human CD49c antibody.HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)

    Flow Cytometry

    Flow-cytometry using anti-human CD49c antibody.KG-1 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

  • Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)

    Flow Cytometry

    Flow-cytometry using anti-human CD49c antibody.MG-63 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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