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Anti-Human CD53 Recombinant Antibody (SAA1593) (HB750013)

Anti-Human CD53 Recombinant Antibody (SAA1593)
Anti-Human CD53 Recombinant Antibody (SAA1593)
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  • 1mg
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Aperçu
Numéro de catalogueHB750013
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA1593
Cible CD53, Tetraspanin-25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tspan-25, TSPAN25, MOX44
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P19397
RRID Anti-Human CD53 Antibody (SAA1593) (abinScience Cat# HB750013, RRID:AB_3727354)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Leukocyte surface antigen CD53 is a ~24 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Plays a role in the activation of monocytes and B-cells. Acts as an essential regulator of B-cell development by promoting interleukin-7 receptor/IL7R signaling. Also promotes, in B-cells, the BCR signaling by recruiting PKC to the plasma membrane in order to phosphorylate its substrates.

1. Zuidscherwoude, M. et al. (2017) Science signaling 10. PMID: 28487417
2. Yang, Y. et al. (2020) The EMBO journal 39, e105246. PMID: 32974937
3. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951
4. Olweus, J. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 707-16. PMID: 8335905
Note For research use only.
Images
  • Anti-Human CD53 Recombinant Antibody (SAA1593)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD53 Antibody (SAA1593)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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