Please ensure Javascript is enabled for purposes of website accessibility
Inicio > Productos > Anticuerpos > Anticuerpos para Citometría de Flujo

Anti-Human CD59 Recombinant Antibody (TS59) (HB615107)

Anti-Human CD59 Recombinant Antibody (TS59)
Anti-Human CD59 Recombinant Antibody (TS59)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
Contáctenos
  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHB615107
Reactividad de especiesHuman
AplicacionesFCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonTS59
Objetivo MSK21, MAC-inhibitory protein, MEM43 antigen, MAC-IP, MIN2, MIRL, HRF20, Protectin, 1F5 antigen, MIC11, MIN3, Membrane inhibitor of reactive lysis, MACIF, 20 kDa homologous restriction factor, CD59, MIN1, CD59 glycoprotein, HRF-20, Membrane attack complex inhibition factor
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P13987
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

CD59 glycoprotein is a ~14 kDa protein. Potent inhibitor of the complement membrane attack complex (MAC) action, which protects human cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore.

1. Farkas, I. et al. (2002) The Journal of physiology 539, 537-45. PMID: 11882685
2. Meri, S. et al. (1990) Immunology 71, 1-9. PMID: 1698710
3. Okada, H. et al. (1989) Biochemical and biophysical research communications 162, 1553-9. PMID: 2475111
4. Davies, A. et al. (1989) The Journal of experimental medicine 170, 637-54. PMID: 2475570
5. Sugita, Y. et al. (1989) Journal of biochemistry 106, 555-7. PMID: 2606909
6. Bodian, DL. et al. (1997) The Journal of experimental medicine 185, 507-16. PMID: 9053451
7. Couves, EC. et al. (2023) Nature communications 14, 890. PMID: 36797260
Nota For research use only.
Imágenes
  • Anti-Human CD59 Recombinant Antibody (TS59)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD59 Antibody (TS59)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recomendación

Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.

Correo: [email protected]

Lista de distribuidores