Anti-Human CD59 Polyclonal Antibody (HB615044)

Name: Anti-Human CD59 Polyclonal Antibody
Brand: abinScience
SKU: HB615044
Price: 168 USD
Availability: InStock

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Especificación:

50ug
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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB615044

Descripción

Anti-Human CD59 Polyclonal Antibody (HB615044) is a rabbit polyclonal antibody detecting CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59; CD59; MIC11; MIN1; MIN2; MIN3; MSK21 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human CD59 (Ser25-Pro128).

Objetivo

CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59; CD59; MIC11; MIN1; MIN2; MIN3; MSK21

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

P13987

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

CD59 glycoprotein is a ~14 kDa protein. Potent inhibitor of the complement membrane attack complex (MAC) action, which protects human cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore.

1. Farkas, I. et al. (2002) The Journal of physiology 539, 537-45. PMID: 11882685

2. Meri, S. et al. (1990) Immunology 71, 1-9. PMID: 1698710

3. Okada, H. et al. (1989) Biochemical and biophysical research communications 162, 1553-9. PMID: 2475111

4. Davies, A. et al. (1989) The Journal of experimental medicine 170, 637-54. PMID: 2475570

5. Sugita, Y. et al. (1989) Journal of biochemistry 106, 555-7. PMID: 2606909

6. Bodian, DL. et al. (1997) The Journal of experimental medicine 185, 507-16. PMID: 9053451

7. Couves, EC. et al. (2023) Nature communications 14, 890. PMID: 36797260

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human CD59 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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