Anti-Human Integrin beta 3/CD61 Monoclonal Antibody (1A470) (HY323025)

Name: Anti-Human Integrin beta 3/CD61 Monoclonal Antibody (1A470)
Brand: abinScience
SKU: HY323025
Price: 106 USD
Availability: InStock

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Каталожный номер	HY323025
Описание	Anti-Human CD61/ITGB3 Monoclonal Antibody (1A470) [1A470] (HY323025) is a mouse monoclonal antibody detecting ITGB3 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Реактивность видов	Human
Применения	ELISA, IHC, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG
ID клона	1A470
Иммуноген	E. coli - derived recombinant human CD61/ITGB3 (Glu134-Glu384).
Цель	Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD61, ITGB3
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P05106
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Integrin beta-3 (CD61/ITGB3) is a ~87 kDa protein. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. 1. Si-Tahar, M. et al. (1997) The Journal of biological chemistry 272, 11636-47. PMID: 9111081 2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 3. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099 4. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 5. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324 6. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677 7. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119 8. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464 9. Takada, YK. et al. (2017) The Journal of biological chemistry 292, 20067-20075. PMID: 29030430 10. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536
Примечание	For research use only.

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Anti-Human Integrin beta 3/CD61 Monoclonal Antibody (1A470).pdf

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Anti-Human Integrin beta 3/CD61 Monoclonal Antibody (1A470) (HY323025)

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