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Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43) (HY546063)

Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43)
Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43)
Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43)
Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43)
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概要
カタログ番号HY546063
説明
Anti-Human CD66e/CEA/CEACAM5 Nanobody (C43) [C43] (HY546063) is a alpaca monoclonal antibody detecting CEACAM5 in ELISA, FuncS. Suitable for Human.
種反応性Human
アプリケーションELISA, FuncS
宿主種Alpaca
クローン性Monoclonal
アイソタイプVHH-8His-Cys-tag
クローンIDC43
ターゲット CD66e, CEA, CEA cell adhesion molecule 5, CEACAM5, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Cell adhesion molecule CEACAM5, Meconium antigen 100
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Purified by Nickel column.
アクセッション番号 P06731
形態 Liquid
保存バッファー 0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:2000-1:20000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.

1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933
2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050
3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308
注意事項 For research use only.
イメージ
  • Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD66e/CEA/CEACAM5 Nanobody (C43)

  • Anti-Human CEACAM-5/CD66e Recombinant Nanobody (C43)

    Bioactivity

    Detects CD66e (Catalog No: HY546011) in indirect ELISA.

参考文献
Formula
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