

| Número de catálogo | HW717013 | ||||
|---|---|---|---|---|---|
| Marca | abinScience | ||||
| Descripción |
Anti-Human CD70 Nanobody (SAA2049) [SAA2049] (HW717013) is a alpaca monoclonal antibody detecting CD70 in ELISA, FCM. Suitable for Human and Cynomolgus.
Highlights
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| Reactividad de especies | Human, Monkey | ||||
| Aplicaciones | ELISA, FCM | ||||
| Especie huésped | Alpaca | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | VHH-8His-Cys-tag | ||||
| ID de clon | SAA2049 | ||||
| Objetivo | CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Purified by Nickel column | ||||
| Número de acceso | P32970 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | CD70 antigen is a ~21 kDa protein. Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. 1. Izawa, K. et al. (2017) The Journal of experimental medicine 214, 73-89. PMID: 28011863 2. Abolhassani, H. et al. (2017) The Journal of experimental medicine 214, 91-106. PMID: 28011864 3. Goodwin, RG. et al. (1993) Cell 73, 447-56. PMID: 8387892 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human CD70 Nanobody (SAA2049)




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