Anti-Human CD27 Ligand/TNFSF7/CD70 Recombinant Nanobody (SAA2049) (HW717013)

Name: Anti-Human CD27 Ligand/TNFSF7/CD70 Recombinant Nanobody (SAA2049)
Brand: abinScience
SKU: HW717013
Price: 126 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HW717013

Marque

abinScience

Description

Anti-Human CD70 Nanobody (SAA2049) [SAA2049] (HW717013) is a alpaca monoclonal antibody detecting CD70 in ELISA, FCM. Suitable for Human and Cynomolgus.

Highlights

●Flow Cytometry — Validated for flow cytometry applications.

Reactivité des espèces

Human, Monkey

Applications

ELISA, FCM

Espèce hôte

Alpaca

Clonalité

Monoclonal

Isotype

VHH-8His-Cys-tag

ID de clone

SAA2049

Cible

CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column

Numéro d'accès

P32970

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

CD70 antigen is a ~21 kDa protein. Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.

1. Izawa, K. et al. (2017) The Journal of experimental medicine 214, 73-89. PMID: 28011863

2. Abolhassani, H. et al. (2017) The Journal of experimental medicine 214, 91-106. PMID: 28011864

3. Goodwin, RG. et al. (1993) Cell 73, 447-56. PMID: 8387892

Note

For research use only.

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