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| カタログ番号 | HW717013 | ||||
|---|---|---|---|---|---|
| ブランド | abinScience | ||||
| 説明 |
Anti-Human CD70 Nanobody (SAA2049) [SAA2049] (HW717013) is a alpaca monoclonal antibody detecting CD70 in ELISA, FCM. Suitable for Human and Cynomolgus.
Highlights
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| 種反応性 | Human, Monkey | ||||
| アプリケーション | ELISA, FCM | ||||
| 宿主種 | Alpaca | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | VHH-8His-Cys-tag | ||||
| クローンID | SAA2049 | ||||
| ターゲット | CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Purified by Nickel column | ||||
| アクセッション番号 | P32970 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | CD70 antigen is a ~21 kDa protein. Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. 1. Izawa, K. et al. (2017) The Journal of experimental medicine 214, 73-89. PMID: 28011863 2. Abolhassani, H. et al. (2017) The Journal of experimental medicine 214, 91-106. PMID: 28011864 3. Goodwin, RG. et al. (1993) Cell 73, 447-56. PMID: 8387892 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD70 Nanobody (SAA2049)
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中国武漢市深敦寺路666号C棟、武漢、430206
