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Anti-Human Transferrin R/TfR Recombinant Antibody (OKT9) (HY036033)

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Спецификация:
  • 50ug
  • 100ug
  • 1mg
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Обзор
Каталожный номерHY036033
Описание
Anti-Human Transferrin R/TfR Recombinant Antibody (OKT9) (HY036033) is a mouse monoclonal antibody detecting Transferrin R/TfR in ELISA, block. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, block
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG1
ID клонаOKT9
Цель CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P02786
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

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Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738
2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240
Примечание For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
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Ссылки
Formula
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Formula
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Stock Solution
C₁ (Stock Conc.)
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Working Solution
C₂ (Working Conc.)
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