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| カタログ番号 | HY570025 |
|---|---|
| 説明 |
Anti-Human CD79α/CD79A Monoclonal Antibody (1A575) [1A575] (HY570025) is a mouse monoclonal antibody detecting CD79a in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, IHC, WB |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | 1A575 |
| 免疫原 | E. coli - derived recombinant human CD79α/CD79A (Met35-Gly219). |
| ターゲット | B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, CD79A |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P11912 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | B-cell antigen receptor complex-associated protein alpha chain (CD79α/CD79A) is a ~25 kDa protein. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD79α/CD79A Monoclonal Antibody (1A575)
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