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Anti-Human CD84/SLAMF5 Recombinant Antibody (SAA0037) (HV297107)

Anti-Human CD84/SLAMF5 Recombinant Antibody (SAA0037)
Anti-Human CD84/SLAMF5 Recombinant Antibody (SAA0037)
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Aperçu
Numéro de catalogueHV297107
Reactivité des espècesHuman
ApplicationsFCM, Neutralization
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a
ID de cloneSAA0037
Cible Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9UIB8
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

SLAM family member 5 (CD84) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process.

1. Martin, M. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3668-76. PMID: 11564780
2. Tangye, SG. et al. (2002) European journal of immunology 32, 1640-9. PMID: 12115647
3. Tangye, SG. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 2485-95. PMID: 12928397
4. Zaiss, M. et al. (2003) Experimental hematology 31, 798-805. PMID: 12962726
5. Nanda, N. et al. (2005) Blood 106, 3028-34. PMID: 16037392
6. Álvarez-Errico, D. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 5577-86. PMID: 22068234
7. Agod, Z. et al. (2018) Frontiers in immunology 9, 62. PMID: 29434592
Note For research use only.
Images
  • Anti-Human CD84/SLAMF5 Recombinant Antibody (SAA0037)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD84 Antibody (ABS1681).

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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