中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HV297107 |
|---|---|
| 種反応性 | Human |
| アプリケーション | FCM, Neutralization |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a |
| クローンID | SAA0037 |
| ターゲット | Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q9UIB8 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | SLAM family member 5 (CD84) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process. 1. Martin, M. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3668-76. PMID: 11564780 2. Tangye, SG. et al. (2002) European journal of immunology 32, 1640-9. PMID: 12115647 3. Tangye, SG. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 2485-95. PMID: 12928397 4. Zaiss, M. et al. (2003) Experimental hematology 31, 798-805. PMID: 12962726 5. Nanda, N. et al. (2005) Blood 106, 3028-34. PMID: 16037392 6. Álvarez-Errico, D. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 5577-86. PMID: 22068234 7. Agod, Z. et al. (2018) Frontiers in immunology 9, 62. PMID: 29434592 |
| 注意事項 | For research use only. |
SEC-HPLC detection for Anti-Human CD84 Antibody (ABS1681).
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
