

| Каталожный номер | HV297024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human CD84 Polyclonal Antibody (HV297024) is a rabbit polyclonal antibody detecting CD84 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CD84 (Lys22-Gly225). | ||||||||
| Цель | Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9UIB8 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | SLAM family member 5 (CD84) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process. 1. Martin, M. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3668-76. PMID: 11564780 2. Tangye, SG. et al. (2002) European journal of immunology 32, 1640-9. PMID: 12115647 3. Tangye, SG. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 2485-95. PMID: 12928397 4. Zaiss, M. et al. (2003) Experimental hematology 31, 798-805. PMID: 12962726 5. Nanda, N. et al. (2005) Blood 106, 3028-34. PMID: 16037392 6. Álvarez-Errico, D. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 5577-86. PMID: 22068234 7. Agod, Z. et al. (2018) Frontiers in immunology 9, 62. PMID: 29434592 | ||||||||
| Примечание | For research use only. |




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