Anti-Human CD85j/LILRB1/ILT2 Recombinant Antibody (SAA0402), APC (HV631137)

Name: Anti-Human CD85j/LILRB1/ILT2 Recombinant Antibody (SAA0402), APC
Brand: abinScience
SKU: HV631137
Price: 290 USD
Availability: InStock

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Каталожный номер	HV631137
Реактивность видов	Human
Применения	ELISA, FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	SAA0402
Конъюгация	APC
Цель	LIR1, Immunoglobulin-like transcript 2, MIR7, CD85 antigen-like family member J, Monocyte/macrophage immunoglobulin-like receptor 7, ILT-2, Leukocyte immunoglobulin-like receptor subfamily B member 1, LIR-1, CD85j, ILT2, LILRB1, MIR-7, Leukocyte immunoglobulin-like receptor 1
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Номер доступа	Q8NHL6
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Leukocyte immunoglobulin-like receptor subfamily B member 1 (CD85j/LILRB1) is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.