Anti-Human CD85j/LILRB1/ILT2 Recombinant Antibody (SAA0402), PE (HV631127)

Name: Anti-Human CD85j/LILRB1/ILT2 Recombinant Antibody (SAA0402), PE
Brand: abinScience
SKU: HV631127
Price: 290 USD
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Número de catálogo	HV631127
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	SAA0402
Conjugación	PE
Objetivo	LIR1, Immunoglobulin-like transcript 2, MIR7, CD85 antigen-like family member J, Monocyte/macrophage immunoglobulin-like receptor 7, ILT-2, Leukocyte immunoglobulin-like receptor subfamily B member 1, LIR-1, CD85j, ILT2, LILRB1, MIR-7, Leukocyte immunoglobulin-like receptor 1
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Número de acceso	Q8NHL6
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Leukocyte immunoglobulin-like receptor subfamily B member 1 (CD85j/LILRB1) is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. _x005F_x000D_ _x005F_x000D_ 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 _x005F_x000D_ _x005F_x000D_ 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 _x005F_x000D_ _x005F_x000D_ 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 _x005F_x000D_ _x005F_x000D_ 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 _x005F_x000D_ _x005F_x000D_ 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 _x005F_x000D_ _x005F_x000D_ 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 _x005F_x000D_ _x005F_x000D_ 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 _x005F_x000D_ _x005F_x000D_ 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.