

| Numéro de catalogue | HC475013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| ID de clone | SAA1580 | ||||
| Cible | APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor | ||||
| Niveau d'endotoxines | < 10 EU/mg | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q07954 | ||||
| RRID | Anti-Human CD91/LRP1 Antibody (SAA1580) (abinScience Cat# HC475013, RRID:AB_3727341) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. 1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044 2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657 3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392 4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438 5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178 6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553 7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD91/LRP1 Antibody (SAA1580)



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