

| Каталожный номер | HC475013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a, kappa | ||||
| ID клона | SAA1580 | ||||
| Цель | APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor | ||||
| Уровень эндотоксинов | < 10 EU/mg | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q07954 | ||||
| RRID | Anti-Human CD91/LRP1 Antibody (SAA1580) (abinScience Cat# HC475013, RRID:AB_3727341) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. 1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044 2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657 3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392 4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438 5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178 6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553 7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371 | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human CD91/LRP1 Antibody (SAA1580)



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