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Anti-Human Fas/TNFRSF6/CD95 Recombinant Antibody (SAA0040), APC (HB873137)

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Vista general
Número de catálogoHB873137
Reactividad de especiesHuman
AplicacionesFCM
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonSAA0040
ConjugaciónAPC
Objetivo APT1, TNFRSF6, FAS1, FASLG receptor, CD95, Apo-1 antigen, Tumor necrosis factor receptor superfamily member 6, FAS, Apoptosis-mediating surface antigen FAS
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Número de acceso P25445
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Working Solution
C₂ (Working Conc.)
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