

| Número de catálogo | HP975014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human CDCA2 Polyclonal Antibody (HP975014) is a rabbit polyclonal antibody detecting CDCA2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CDCA2 (Ala383-Glu441). | ||||||||
| Objetivo | Repo-Man, Recruits PP1 onto mitotic chromatin at anaphase protein, CDCA2, Cell division cycle-associated protein 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q69YH5 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Cell division cycle-associated protein 2 (CDCA2) is a ~112 kDa protein. Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phosphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. | ||||||||
| Nota | For research use only. |
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