Anti-Human CDKN2A/p16INK4a Recombinant Nanobody (SAA2259) (HW820013)

Name: Anti-Human CDKN2A/p16INK4a Recombinant Nanobody (SAA2259)
Brand: abinScience
SKU: HW820013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW820013

Description

Anti-Human CDKN2A/p16INK4a Nanobody (SAA2259) [SAA2259] (HW820013) is a alpaca monoclonal antibody detecting CDKN2A/p16INK4a in ELISA. Suitable for Human.

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Alpaca

Clonalité

Monoclonal

Isotype

VHH-His

ID de clone

SAA2259

Cible

CDKN2A/p16INK4a

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>90% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q8N726

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

Tumor suppressor ARF, Alternative reading frame, ARF, Cyclin-dependent kinase inhibitor 2A, p14ARF, CDKN2A

Contexte

Tumor suppressor ARF (CDKN2A/p16INK4a) is a ~13 kDa protein. Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CDKN2A/p16INK4a Nanobody (SAA2259)

Reférences

Fiche technique

Anti-Human CDKN2A/p16INK4a Recombinant Nanobody (SAA2259).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai