

| Número de catálogo | HF842014 | ||||||||
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| Descripción |
Anti-Human CDS2 Polyclonal Antibody (HF842014) is a rabbit polyclonal antibody detecting CDS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CDS2 (Ser282-Ser339). | ||||||||
| Objetivo | Phosphatidate cytidylyltransferase 2, CDP-diglyceride pyrophosphorylase 2, CDS2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDP-DAG synthase 2, CDP-diglyceride synthase 2, CDS 2, CTP:phosphatidate cytidylyltransferase 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O95674 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Phosphatidate cytidylyltransferase 2 (CDS2) is a ~51 kDa protein. Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. 1. D'Souza, K. et al. (2014) Biochemistry 53, 7358-67. PMID: 25375833 2. Qi, Y. et al. (2016) Journal of lipid research 57, 767-80. PMID: 26946540 3. Xu, Y. et al. (2019) The Journal of biological chemistry 294, 16740-16755. PMID: 31548309 | ||||||||
| Nota | For research use only. |
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