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| カタログ番号 | HF842014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CDS2 Polyclonal Antibody (HF842014) is a rabbit polyclonal antibody detecting CDS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CDS2 (Ser282-Ser339). | ||||||||
| ターゲット | Phosphatidate cytidylyltransferase 2, CDP-diglyceride pyrophosphorylase 2, CDS2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDP-DAG synthase 2, CDP-diglyceride synthase 2, CDS 2, CTP:phosphatidate cytidylyltransferase 2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95674 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Phosphatidate cytidylyltransferase 2 (CDS2) is a ~51 kDa protein. Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. 1. D'Souza, K. et al. (2014) Biochemistry 53, 7358-67. PMID: 25375833 2. Qi, Y. et al. (2016) Journal of lipid research 57, 767-80. PMID: 26946540 3. Xu, Y. et al. (2019) The Journal of biological chemistry 294, 16740-16755. PMID: 31548309 | ||||||||
| 注意事項 | For research use only. |
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