

| Каталожный номер | HF842014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human CDS2 Polyclonal Antibody (HF842014) is a rabbit polyclonal antibody detecting CDS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CDS2 (Ser282-Ser339). | ||||||||
| Цель | Phosphatidate cytidylyltransferase 2, CDP-diglyceride pyrophosphorylase 2, CDS2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDP-DAG synthase 2, CDP-diglyceride synthase 2, CDS 2, CTP:phosphatidate cytidylyltransferase 2 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O95674 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Phosphatidate cytidylyltransferase 2 (CDS2) is a ~51 kDa protein. Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. 1. D'Souza, K. et al. (2014) Biochemistry 53, 7358-67. PMID: 25375833 2. Qi, Y. et al. (2016) Journal of lipid research 57, 767-80. PMID: 26946540 3. Xu, Y. et al. (2019) The Journal of biological chemistry 294, 16740-16755. PMID: 31548309 | ||||||||
| Примечание | For research use only. |
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