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Anti-Human CECR2 IP Recombinant Antibody (SAA0196) (HP125013)

Anti-Human CECR2 IP Recombinant Antibody (SAA0196)
Anti-Human CECR2 IP Recombinant Antibody (SAA0196)
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Aperçu
Numéro de catalogueHP125013
Reactivité des espècesHuman
ApplicationsELISA, IF, IP
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a
ID de cloneSAA0196
Cible CECR2, Cat eye syndrome critical region protein 2, KIAA1740
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9BXF3
RRID Anti-Human CECR2 IP Antibody (SAA0196) (abinScience Cat# HP125013, RRID:AB_3729730)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Chromatin remodeling regulator CECR2 is a ~164 kDa protein. Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The complexes do not have the ability to slide mononucleosomes to the center of a DNA template. The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex. Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes.

1. Banting, GS. et al. (2005) Human molecular genetics 14, 513-24. PMID: 15640247
2. Filippakopoulos, P. et al. (2012) Cell 149, 214-31. PMID: 22464331
3. Flynn, EM. et al. (2015) Structure (London, England : 1993) 23, 1801-1814. PMID: 26365797
4. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535
5. Liu, L. et al. (2002) Genomics 79, 124-36. PMID: 11827465
Note For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
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  • Anti-Human CECR2 IP Recombinant Antibody (SAA0196)

    SDS-PAGE

    SDS-PAGE for Anti-Human CECR2 IP Antibody (SAA0196).

Reférences
Formula
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Recommandation

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