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| カタログ番号 | HF856014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CELF2 (Lys41-Asp211). | ||||||||
| ターゲット | CELF-2, hNAPOR, Neuroblastoma apoptosis-related RNA-binding protein, CUGBP Elav-like family member 2, CUG-BP- and ETR-3-like factor 2, BRUNOL3, NAPOR, ETR3, CUGBP2, CUG triplet repeat RNA-binding protein 2, ETR-3, CELF2, ELAV-type RNA-binding protein 3, RNA-binding protein BRUNOL-3, Bruno-like protein 3, CUG-BP2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95319 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | CUGBP Elav-like family member 2 (CELF2) is a ~54 kDa protein. RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. 1. Treiber, T. et al. (2017) Molecular cell 66, 270-284.e13. PMID: 28431233 | ||||||||
| 注意事項 | For research use only. |
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