Anti-Human CEP19 Polyclonal Antibody (HP542014)

Name: Anti-Human CEP19 Polyclonal Antibody
Brand: abinScience
SKU: HP542014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HP542014

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CEP19 (Met1-Asp133).

Cible

Centrosomal protein of 19 kDa, C3orf34, Cep19, CEP19

Purification

Purified by antigen affinity column.

Numéro d'accès

Q96LK0

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Centrosomal protein of 19 kDa (CEP19) is a ~19 kDa protein. Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring to the centrosomes.

1. Nishijima, Y. et al. (2017) Molecular biology of the cell 28, 1652-1666. PMID: 28428259

2. Kanie, T. et al. (2017) Developmental cell 42, 22-36.e12. PMID: 28625565

3. Mojarad, BA. et al. (2017) Open biology 7. PMID: 28659385

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human CEP19 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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