

| Numéro de catalogue | HP304014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CEP72 (Glu12-Lys130). | ||||||||
| Cible | CEP72, KIAA1519, Cep72, Centrosomal protein of 72 kDa | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9P209 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Centrosomal protein of 72 kDa (CEP72) is a ~71 kDa protein. Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2. 1. Oshimori, N. et al. (2009) The EMBO journal 28, 2066-76. PMID: 19536135 2. Kodani, A. et al. (2015) eLife 4. PMID: 26297806 | ||||||||
| Note | For research use only. |
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