

| Número de catálogo | HB693014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human CES1 Polyclonal Antibody (HB693014) is a rabbit polyclonal antibody detecting CES1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CES1 (Gly18-Leu299). | ||||||||
| Objetivo | Serine esterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, Liver carboxylesterase 1, REH, Methylumbelliferyl-acetate deacetylase 1, HMSE, ACAT, hCE-1, Acyl-coenzyme A:cholesterol acyltransferase, CE-1, Brain carboxylesterase hBr1, CEH, SES1, CES2, Cholesteryl ester hydrolase, Triacylglycerol hydrolase, Cocaine carboxylesterase, TGH, Carboxylesterase 1, CES1, Egasyn | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P23141 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Liver carboxylesterase 1 (CES1) is a ~62 kDa protein. Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. 1. Crow, JA. et al. (2008) Biochimica et biophysica acta 1781, 643-54. PMID: 18762277 2. Brzezinski, MR. et al. (1994) Biochemical pharmacology 48, 1747-55. PMID: 7980644 3. Pindel, EV. et al. (1997) The Journal of biological chemistry 272, 14769-75. PMID: 9169443 4. Schindler, R. et al. (1998) European journal of biochemistry 251, 863-73. PMID: 9490062 5. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 | ||||||||
| Nota | For research use only. |
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