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| カタログ番号 | HB693014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human CES1 Polyclonal Antibody (HB693014) is a rabbit polyclonal antibody detecting CES1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CES1 (Gly18-Leu299). | ||||||||
| ターゲット | Serine esterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, Liver carboxylesterase 1, REH, Methylumbelliferyl-acetate deacetylase 1, HMSE, ACAT, hCE-1, Acyl-coenzyme A:cholesterol acyltransferase, CE-1, Brain carboxylesterase hBr1, CEH, SES1, CES2, Cholesteryl ester hydrolase, Triacylglycerol hydrolase, Cocaine carboxylesterase, TGH, Carboxylesterase 1, CES1, Egasyn | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P23141 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Liver carboxylesterase 1 (CES1) is a ~62 kDa protein. Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. 1. Crow, JA. et al. (2008) Biochimica et biophysica acta 1781, 643-54. PMID: 18762277 2. Brzezinski, MR. et al. (1994) Biochemical pharmacology 48, 1747-55. PMID: 7980644 3. Pindel, EV. et al. (1997) The Journal of biological chemistry 272, 14769-75. PMID: 9169443 4. Schindler, R. et al. (1998) European journal of biochemistry 251, 863-73. PMID: 9490062 5. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 | ||||||||
| 注意事項 | For research use only. |
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