

| Каталожный номер | HB693014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human CES1 Polyclonal Antibody (HB693014) is a rabbit polyclonal antibody detecting CES1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CES1 (Gly18-Leu299). | ||||||||
| Цель | Serine esterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, Liver carboxylesterase 1, REH, Methylumbelliferyl-acetate deacetylase 1, HMSE, ACAT, hCE-1, Acyl-coenzyme A:cholesterol acyltransferase, CE-1, Brain carboxylesterase hBr1, CEH, SES1, CES2, Cholesteryl ester hydrolase, Triacylglycerol hydrolase, Cocaine carboxylesterase, TGH, Carboxylesterase 1, CES1, Egasyn | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P23141 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Liver carboxylesterase 1 (CES1) is a ~62 kDa protein. Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. 1. Crow, JA. et al. (2008) Biochimica et biophysica acta 1781, 643-54. PMID: 18762277 2. Brzezinski, MR. et al. (1994) Biochemical pharmacology 48, 1747-55. PMID: 7980644 3. Pindel, EV. et al. (1997) The Journal of biological chemistry 272, 14769-75. PMID: 9169443 4. Schindler, R. et al. (1998) European journal of biochemistry 251, 863-73. PMID: 9490062 5. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 | ||||||||
| Примечание | For research use only. |
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