

| Numéro de catalogue | HT236014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human CES2 Polyclonal Antibody (HT236014) is a rabbit polyclonal antibody detecting CES2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CES2 (His452-Leu559). | ||||||||
| Cible | Cocaine esterase, CES2, Carboxylesterase 2, CE-2, ICE, Methylumbelliferyl-acetate deacetylase 2, hCE-2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O00748 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Cocaine esterase (CES2) is a ~61 kDa protein. Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. 1. Pindel, EV. et al. (1997) The Journal of biological chemistry 272, 14769-75. PMID: 9169443 2. Lian, J. et al. (2018) Protein & cell 9, 178-195. PMID: 28677105 3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 | ||||||||
| Note | For research use only. |
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