中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HF634013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human Complement Factor B Recombinant Antibody (SAA1512) (HF634013) is a mouse monoclonal antibody detecting Complement Factor B in ELISA. Suitable for Human.
Highlights
|
||||
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1512 | ||||
| ターゲット | Properdin factor B, Complement factor B, GBG, Glycine-rich beta glycoprotein, BFD, C3/C5 convertase, CFB, PBF2, BF | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P00751 | ||||
| RRID | Anti-Human CFB Antibody (SAA1512) (abinScience Cat# HF634013, RRID:AB_3727273) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Complement factor B (CFB) is a ~85 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases. 1. Pangburn, MK. et al. (1986) The Biochemical journal 235, 723-30. PMID: 3638964 2. Vogt, W. et al. (1978) Immunology 34, 29-40. PMID: 624565 3. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279 4. Vogel, CW. et al. (1982) The Journal of biological chemistry 257, 8292-9. PMID: 6919543 5. Hourcade, DE. et al. (1998) The Journal of biological chemistry 273, 25996-6000. PMID: 9748277 6. Niemann, MA. et al. (1980) Biochemistry 19, 1576-83. PMID: 6769474 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human CFB Antibody (SAA1512)
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
