Anti-Human CHCHD3 Polyclonal Antibody (HP686014)

Name: Anti-Human CHCHD3 Polyclonal Antibody
Brand: abinScience
SKU: HP686014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HP686014

Description

Anti-Human CHCHD3 Polyclonal Antibody (HP686014) is a rabbit polyclonal antibody detecting CHCHD3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CHCHD3 (Ser58-Gly227).

Cible

MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, MINOS3, MIC19, CHCHD3

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9NX63

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

MICOS complex subunit MIC19 (CHCHD3) is a ~26 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.

1. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180

2. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732

3. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824

4. Liu, H. et al. (2012) PloS one 7, e34832. PMID: 22567091

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CHCHD3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: Hela cell lysate
Lane 3: Jurkat cell lysate
Lane 4: Hepg2 cell lysate
Lane 5: A549 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse kidney lysate
Lane 8: Mouse liver lysate
Lane 9: Mouse heart lysate
Lane 10: Rat kidney lysate
Lane11: Rat Liver lysate
Lane12: Rat heart lysate

Reférences

Fiche technique

Anti-Human CHCHD3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human CHCHD3 Polyclonal Antibody (HP686014)

Aperçu

Images

Reférences

Fiche technique

SDS