Anti-Human CHCHD3 Polyclonal Antibody (HP686014)

Name: Anti-Human CHCHD3 Polyclonal Antibody
Brand: abinScience
SKU: HP686014
Price: 96 USD
Availability: InStock

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Каталожный номер

HP686014

Описание

Anti-Human CHCHD3 Polyclonal Antibody (HP686014) is a rabbit polyclonal antibody detecting CHCHD3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CHCHD3 (Ser58-Gly227).

Цель

MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, MINOS3, MIC19, CHCHD3

Очистка

Purified by antigen affinity column.

Номер доступа

Q9NX63

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

MICOS complex subunit MIC19 (CHCHD3) is a ~26 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.

1. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180

2. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732

3. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824

4. Liu, H. et al. (2012) PloS one 7, e34832. PMID: 22567091

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-CHCHD3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: Hela cell lysate
Lane 3: Jurkat cell lysate
Lane 4: Hepg2 cell lysate
Lane 5: A549 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse kidney lysate
Lane 8: Mouse liver lysate
Lane 9: Mouse heart lysate
Lane 10: Rat kidney lysate
Lane11: Rat Liver lysate
Lane12: Rat heart lysate

Ссылки

Даташит

Anti-Human CHCHD3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human CHCHD3 Polyclonal Antibody (HP686014)

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