

| Número de catálogo | HT401014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CHD1 (Ser1127-Thr1285). | ||||||||
| Objetivo | ATP-dependent helicase CHD1, CHD1, Chromodomain-helicase-DNA-binding protein 1, CHD-1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O14646 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | ATP-dependent chromatin remodeler CHD1 is a ~196 kDa protein. ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. 1. Sims, RJ. et al. (2007) Molecular cell 28, 665-76. PMID: 18042460 2. Pilarowski, GO. et al. (2018) Journal of medical genetics 55, 561-566. PMID: 28866611 | ||||||||
| Nota | For research use only. |
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